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Data: Good

Glycyrrhiza Glabra (Licorice) Root Extract

Other Concerns

Neurotoxicity (low), Endocrine disruption (moderate), Non-reproductive organ system toxicity (low_moderate), and Irritation (skin, eyes, or lungs) (low)

SYNONYMS

● GLYCYRRHIZA GLABRA ROOT EXTRACT
● LICORICE, GLYCYRRHIZA GLABRA, EXT.
● GLYCYRRHIZA GLABRA EXTRACT
● GLYCYRRHIZA FLAVONOIDS
● GLYCYRRHIZA EXTRACTED POWDER
● GLYCYRRHIZA EXTRACT
● EXTRACT OF LICORICE
● EXTRACT OF GLYCYRRHIZA GLABRA
● GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Glycyrrhiza Glabra (Licorice) Root Extract is an extract of the root of the licorice, Glycyrrhizaglabra.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW_MODERATE
    Allergies & Immunotoxicity
  • LOW_MODERATE
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

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Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Limited evidence of skin irritationCosmetic Ingredient Review (CIR)

Endocrine disruption

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CONCERN REFERENCE
Human adrenal disruptor - strong evidenceToxicological Effects of Glycyrrhiza glabra (Licorice): A Review(2017-11-01)
Limited evidence of estrogen disruptionEstrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture(1997-04-01)
Human disruptor - moderate evidenceAn update on plant derived anti-androgens(2012-01-01)
Human adrenal disruptor - strong evidenceBioactive Candy: Effects of Licorice on the Cardiovascular System(2019-10-01)
One or more animal studies show endocrine disruption at moderate dosesInduction of growth hormone release by glycyrrhizae radix on rat(2007-11-01)

Developmental/reproductive toxicity

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CONCERN REFERENCE
One or more animal studies show male reproductive system effects at moderate dosesToxicological Effects of Glycyrrhiza glabra (Licorice): A Review(2017-11-01)
Human reproductive/developmental toxicant - moderate evidenceToxicological Effects of Glycyrrhiza glabra (Licorice): A Review(2017-11-01)

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Associated with hepatic toxicityToxicological Effects of Glycyrrhiza glabra (Licorice): A Review(2017-11-01)
Limited evidence of liver toxicityToxicological Effects of Glycyrrhiza glabra (Licorice): A Review(2017-11-01)
Possible human cardiovascular toxicantBioactive Candy: Effects of Licorice on the Cardiovascular System(2019-10-01)

Neurotoxicity

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CONCERN REFERENCE
One or more animal studies show nervous system effects at high dosesLiquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review(2018-12-01)

Allergies/immunotoxicity

Expand content Collapse content
CONCERN REFERENCE
One or more animal studies show immune system or allergenic effects at low dosesLiquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review(2018-12-01)
  • Cosmetic Ingredient Review (CIR)
  • Toxicological Effects of Glycyrrhiza glabra (Licorice): A Review(2017-11-01)
  • Estrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture(1997-04-01)
  • An update on plant derived anti-androgens(2012-01-01)
  • Bioactive Candy: Effects of Licorice on the Cardiovascular System(2019-10-01)
  • Induction of growth hormone release by glycyrrhizae radix on rat(2007-11-01)
  • Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review(2018-12-01)

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.


HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG Verified® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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