|
According to the Danish centre on endocrine disruptors this substance is an endocrine disruptor.
|
some
|
Ulla Hass. 2018. Danish centre on endocrine disruptors: List of Endocrine Disrupting Chemicals. DTU National Food Institute.
|
|
This substance may cause developmental and reproductive toxicity.
|
some
|
2021. ECHA Assessment of regulatory needs: Salicylate esters. European Chemicals Agency.
|
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
NTP Toxcast scored 1.5-2.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
The Cosmetic Ingredient Review Panel concluded this substance is safe for use when formulated to be non-sensitizing.
|
some
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
NTP Toxcast scored 1.5-2.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
|
The Cosmetic Ingredient Review panel concludes this substance is safe for use when formulated to be non-irritating.
|
some
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
Hexyl salicylate caused skin irritation in animals.
|
some
|
Nada Oršolić, Jadranka Skurić, Domagoj Dikić & Gabrijela Stanić. 2014. Inhibitory effect of a propolis on di-n-propyl disulfide or n-hexyl salycilate-induced skin irritation, oxidative stress and inflammatory responses in mice. Fitoterapia 93, 18-30.
|
|
The Cosmetic Ingredient Review Panel concluded this substance is safe for use when formulated to be non-sensitizing.
|
some
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
Skin sensitization observed in animal testing.
|
some
|
A. Lapczynski, L. Jones, D. McGinty, S. Bhatia, C. S. Letizia & A. M. Api. 2007. Fragrance material review on hexyl salicylate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 45 Suppl 1, S410-7.
|
|
This substance is predicted to be genotoxic
|
some
|
Environmental Protection Agency (EPA): CompTox Chemicals Dashboard
|
|
The Cosmetic Ingredient Review panel concludes this substance is safe for use when formulated to be non-irritating.
|
some
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
Equivocal evidence of minor skin irritation in human and animal studies.
|
low
|
A. Lapczynski, L. Jones, D. McGinty, S. Bhatia, C. S. Letizia & A. M. Api. 2007. Fragrance material review on hexyl salicylate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 45 Suppl 1, S410-7.
|
|
This substance may cause developmental and reproductive toxicity.
|
low
|
2021. ECHA Assessment of regulatory needs: Salicylate esters. European Chemicals Agency.
|
|
No evidence of skin sensitization in limited human testing.
|
low
|
Niels H. Bennike, Claus Zachariae & Jeanne D. Johansen. 2019. Optimal patch test concentration for three widely used sensitizing fragrance substances without mandatory labelling in cosmetics. Contact dermatitis 80(5), 325-327.
|
|
European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
|
low
|
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
|
|
The European Commission's Scientific Committee on Consumer Safety reports this substance shows negative results for causing contact allergy in humans.
|
low
|
EU Cosmetics Directive: Opinion on Frangrance allergens in cosmetics (2011)
|
|
The European Union Ecolabel program reports this substance is readily biodegradable.
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
This substance may cause developmental and reproductive toxicity.
|
low
|
2021. ECHA Assessment of regulatory needs: Salicylate esters. European Chemicals Agency.
|
|
This substance may cause developmental and reproductive toxicity.
|
low
|
2021. ECHA Assessment of regulatory needs: Salicylate esters. European Chemicals Agency.
|
